(From Science Vol 373 Issue 6560, September 10, 2021) Li et al. found that cocaine SA in mice that express a SERT that blocks cocaine binding (SertKI mice) (8) does not increase extracellular serotonin concentrations, but unexpectedly, this causes increased transition to compulsion compared with that in wild-type (WT) mice. The population of perseverers of SertKI mice in cocaine SA is comparable with that of WT mice in the oDASS group. The authors also found that although oDA

Notion Page link: here The video on right shows spontaneous seizure in a MgPTX mouse. (Supplementary Video 4 in the paper)